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pentobarbital will decrease the extent or outcome of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with strong CYP3A4 inducers is not really encouragedEstradiol, estrone, progesterone and other steroidal hormones: Pretreatment with or concurrent administration of phenobarbital could re

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